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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e20299f23597cadfca5480ec63990423a35e05278fdd88feceff349f1a7953b7' 
  AND token = 'MQTkwJXU2mygxPb+ZGrVMXno7R5fabXW2uRcZ9MW+MQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}