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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '801d3a378e29d62bbf982f8f8799e72680f758d8b785c2edb2d538d305b81c34' 
  AND token = 'jiDNfwXcfx3AlfRQbml2ZPV2WrPyMYRajp1+YjD12BE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}