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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '873c61f3e171a523b074bed87d6c961b7d881f91d5478d7205d215ff52cf5b64' 
  AND token = 'rFCT1uCkTyu3HON4ghPnVpg8pSlNj//4KjBd1wN5ocg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}