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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48030b1f1a6e9d6d64f91c010d624b6297e0b1254daafc8d602046343be762e7' 
  AND token = 'lBVcrVyNue4L44EhfsfPJo7PlwV9Me7Ry686qVQbWXQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}