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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc4bd4ae674a3bcefd2a4618bf9243befe5436973626cc955ce4b842ca59c286' 
  AND token = 'h+omE//TCfACwi0Dv6B/xrev9HFDnQk4aiAuIYW/nus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}