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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '864644dfd7ede9415eaf4139ba7158cad5568f4e0293dd2acfa931439a312ec7' 
  AND token = 'zzZxIUNlDfVsm6TA3i3TCahnzMXqL5JH1lM+KXWAu3I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}