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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '151f4d854f3d295f1c6722250c1731801ca9ccd677a63a76ad0475999f8cc83d' 
  AND token = 'IpHXgnz076Uknpxsg0n3M5fpzGfmHoXLcRXFhfUj9xU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}