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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb3e72fec1289111b95c48f78b74dee5e86663f2e2befcdfa8388bdc7cb85c49' 
  AND token = 'rAosNrg662ZJiHvidJ51w4XYxn2d3d0xvOLk8hIXz38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}