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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c193b79f6ec9998c77e7637ca070f7362822663ef19bc96ddec50b9b3da1e017' 
  AND token = 'epu7tA5Hh1aao4EdL4VRz3mmbKX5xtxXh+LnpGicnRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}