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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1671cbdac6049a73228501576a068c0eb18845461931f51585e70c9e71c26aa' 
  AND token = '3YDMk5GLNzU7Jcap1mn1/DWrqVrwtRy6a7TvLVYfb+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}