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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b75fd3285d1b425738eb4e01cd11cf19cc04de5a6d51e6d8f7c80b864636d48' 
  AND token = '3MRiLJ1SG92lOGKmmsqTzVz4G5lo7BPiQUlVg17i6AE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}