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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a4d15ec22d2f3029263dd931e29fdbdd9cdb4f62b617085e990a6250fbfdf4d' 
  AND token = 'LqqrMTMuXIwJ6pf+0QfcaTK4oO7wpUXFs00KDeOhBDA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}