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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd260e1c4366ebb0d4dff60830b384854382fb5897772896b6038ec0c6b0a9e4' 
  AND token = 'MMhuFBaYp3N2xKbxKeZo4N5Z4WgOxeoX9hW7G3lzrRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}