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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '128faec41cecda288170b309730e77fbbe23a2557186faca30685c58e9eed4a3' 
  AND token = 'c3yBe8KnGzKavAiy2CTMX4MS4awgfq+12K2ZgwVBkiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}