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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '284c839d1dfaf70ac692a8221ec303ad147b2353562c071af9414e67a47d350f' 
  AND token = 'Xqifr5SsMEy+OgqhITYFtUqIcfeQcgIJRXAG+Q8mfm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}