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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa5d10de2b6e97c5c9d78ac6347566b5590bbe33d6a7733d53c656a1679614c4' 
  AND token = 'w0xPjc8Ld/bLFDSt+tiVx21+rpZ54GseRhxRkLHUq4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}