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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a45f570547c5c3c5593935b47cdf96e06a2e33444c55c4990ca90e1b698688a0' 
  AND token = 'zv4Ha5Ft9G/K2cOji+s1GGG0HFh5l5cvYrmKFR5Sawk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}