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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3e3e0d3d591bbdfbb40b27bc10ca9800fe9c81c01532e68ba966d97045dda31' 
  AND token = '6/ld2Lew/spEC9NLQEbksDAPIrAzGF9GoriaQxFvq8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}