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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a22529f0bbebfa395415e033c0f5ed9326c22a8286430c4e9501599245097b44' 
  AND token = 'WkpZ7ZYZwWZl5iTL/aXi1/KU4tTu6/vuvpalkgXRSuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}