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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6cc0bfab91902f9798023c4ca6ea46a044e7d76fb811fcd8d9a8d587e04fff1' 
  AND token = 'AkTJD1hMQYGCV7SoENeNILsixOFNx92ivc5q4nRLXKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}