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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33345c491ef77887685ab83f616bba5bd2b7d6f47ab337e01002eed3ef2bb388' 
  AND token = '0Tra0OpwKajRNfiVyP3PoCgjn3jt06FRd5YsFcjIrCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}