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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a58005e0bf8dca9bed66d80586adac2fed0a50493a0d603f706f2bf9064e66bc' 
  AND token = 'HwGf0FbW5q+AHE9aQlrL7sLaPYMIf+IizVpwdQ7E1eQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}