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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c12c81294e9afc2919d788f56d517081213562178e522ec46338d4cd44db00b7' 
  AND token = 'nJsT4iNnV7s1TYiLTFjGPsCoj1xEx+wrsCMa4kvArQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}