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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0d054c2a65cedb857855b1d1e09b3524186ce3edde910870f01740d15a8328d' 
  AND token = 'wdX7IJigO3vBMh44eswtoGyhloV99jsfvej7rmSzhPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}