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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09bc9c0833b350a5e96b936259e0cb16ca9a250ea42fd7cc3471d29469477e11' 
  AND token = 'ILZp9/PTByPUL7Zocu2XcyN3zgAhX6Uwl2pHgiKQWOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}