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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a001125df84ede700deee78749cfdc158b3635c53696ba7854c91b6e3065c61' 
  AND token = 'KzRdzRadfq17uxEGVhDE8N7Jdd9PyvWamgtOirZQxlc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}