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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32efd8287890f8be69f1a00fbfd5a0e8c3052c80ac94b7e0832826cd1ca80121' 
  AND token = 'Dm0k4TKi0PaYkrb2L77lt8Hg3b0pf0ZEI26rJD8yjjU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}