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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0dfc8601c869a28a5ee086165555e28340ace43ee18dba9c9cd1d40ac54a11ea' 
  AND token = 'U9iAmtrIwMttLJ2eXmRviQCMfLsfvinkikHaUEGX9eg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}