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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9297c2d35c83bd79a3d0745d82e12e38153e4b66e22f7b3c7231481e49dbe3c5' 
  AND token = 'j/HSTpAM4GhC21qNubWNyefLQAickKbLwV66JQiRsZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}