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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39132c18734a2d0fd19a965fdce5b350ce86fa3459390b2649f5ddcda000141b' 
  AND token = 'A4nvkuK2ZwDudmW0YN/D/1hSqcFXUUHA7MuCX3iRirk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}