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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd323b804f2ca0eeace61559b85023c168a282233fa924aa62a0042fa497bae6c' 
  AND token = '+ZPFxG9WjD60kL1/XohQVv5TR2Z02Ma8KmbYAq5TfHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}