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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80225fa9a55778a113b91ef2e05021ff7fad6b48e3c231f7a77ccf5d3758f932' 
  AND token = 'X9FqAf/iuf4L9U/MtVuEaxLseq+olXmBbeYb+vouM1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}