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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54ae5c12bc339adae3e3574eb1a328cc2d5d38a9e159162440254c1052bebb30' 
  AND token = 'qvjCDb49oVZ09vezxuR/7vN5pEEwTh0mqUlJO0/pA7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}