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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e05097236b4c2e3fdd9a4e6112cff80fd2165ec4748018c60fdfa514f1a83817' 
  AND token = 'GrKHd2rTu07YVyA51btwfAIU6eEg85VYQAhelxrwM/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}