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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50cd52674613fee3b3cbdce9536ceffe2791d99354d622250f13cad4957b64bf' 
  AND token = 'wMC3yDCI+MRDXrAezQjarXv/n72LZlqw2zaMPm13OsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}