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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b71d22f2b255f6be4df41eb622008530093af1c205cd4b802219c0670bee431f' 
  AND token = 'H7IxJGdYhyV0o9o+NRJ+9JA3x4u19uXc5ujnyvAXmVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}