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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '481be872759da9f13ca9ece7f62699e5142890a48d01ae9b10a7dd94c43da186' 
  AND token = 'wJLbh59ddi3j/Txq61MCM10l2Amwv5ffnGyss9nu9vo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}