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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff1888cbdd0219c614234654902415ad6e4be61297d7c4b2f60fe6ad50ccfa4f' 
  AND token = 'hUiJS3NMtFKs/1c1W39BUDQeJf0QW/xh+DO8QtX76Xk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}