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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '480b89ae04ef9a95a7a23605d1e7b3010431d119c738b7b84fc67300b194a0fc' 
  AND token = 'fBts5yABOQXCcTx0t72SHV9DZvDXbT9ws2YY0IncC4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}