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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '162b19236b609fa8fa3a70a862f66e3cb9df5848d0a4eae0f4a0993e5fcaaee9' 
  AND token = 'P2I5OC6Gkjzstk2sKuV8v/cnPNRr8Dbm2+7HL8rIjkA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}