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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cfc2ed2bea2f7ff5cdea462b652fd4568b60317f9d68c508ed6dab767ff0a48' 
  AND token = 'VMnPmDfL2beFbJlXYamTB78+S3sDl0rOQ7gK7WcC0S4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}