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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df7f179bbed9ac0baa288399a078939989ba29037cf8997f21eaeca1769e151a' 
  AND token = 'aJhED5yzVCE1yPALAThIzX47FUH/b2msgMZ/V3iKf9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}