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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8d06ba8c71e0dff08a4d17d63e007b896eaadf1347997e03b6c808ddb12e62e' 
  AND token = 'KV5I3UEO8gbUDZ7mtG5Mv+JS7P02aNw5P3HFAfTr+Tc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}