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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f489e1f948476311bdcb03261a7c3d1bb86f0e02deb9aa1681822f2eaa772c0' 
  AND token = 'CxAq2wMzeb1KOEo4ELc1TBxyH8FojfC+ThpxQPQmqnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}