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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2aad133c89227741454ab651db99031ab9f8abcabc628aad99ac028c00f8a52' 
  AND token = 'lm3MUf7seOb+9EF6dZr+rac+Oxp4mOSHsMRAu9rqiyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}