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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fb5f2a40c0a600bf110aa5fc5bb12183cb7fbfb1b2d48860de74736d18d7780' 
  AND token = 'RWyEa3QhZPM7jxN0p+6c66V3CDVJ3rnJ5PF9YrwMtQA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}