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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5dbbaf12a630be3104d97d082ba6295507a1449eac536a519163847ae18db3c6' 
  AND token = '8oRFiqp9Cl1kDx/qMx3uCRT4Vb1FqwL1tSHU1Ql6cqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}