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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38f77e34d558b15eb7fc2c107657338ed1ce043b1c21fde0a97cac8d81324973' 
  AND token = 'Rk0jT+33yi6v9XR7ncOG9Qro/dnqI2NOEGRrBRf2Wek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}