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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1dc29e34eb7330507399fac0d536dde957f457a5b04c4e4dd1d8fa9ac2c0dd28' 
  AND token = '+6SdNWZoVk+ybVSAxG4Isw2nczAMAryyAGR82FfmZsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}