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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f389d1bfdccf23e47cd1ae9202c4aa7c7d7b791bbc35c1bc793a3be954a6257' 
  AND token = 'Z69YfRjqSK/mGm1kdfdaNGouxCFibh25qnUUnFMCgNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}